I agree with Todd too...you would have to run that engine up past 7500 rpms to take full advantage of that carb even with ported fuelie heads!
I have a 331 SBC... 10.75 to 1...AFR 195 CC Ported Heads, Team G intake , Holley 800 (I run it up to 7500 rpms) Comp Cams Solid Cam 250 @ .050 with .555 gross lift. I am making about 425 at the crank and thats with some pretty decent heads!
Hope this helps as a reference! Good luck!