You can run the C16 in this engine without a problem, however you will be leaving power on the table. C16 is designed for forced induction engines or nitrous engines not naturally asperated engines. If yougo to VP's website and look at their fuel recomendations you can pick the fuel that you need for the application that you have. also if you still have questions you can call their tech line and they are pretty helpfull. If you run the C16 and the C14 or C14+ back to back on the dyno with this engine combo I will bet the farm that the 14 will make more power and still be very safe against detonation.